Ergonomic and economical pipettors are designed for repeatable, precise, and accurate liquid handling applications. The lightweight design facilitates repetitive procedures and reduces the risk of repetitive strain injury over a prolonged period of use. Pipettors feature an enlarged and streamlined grip that allows them to be kept firmly in hand with little stress. An enlarged push button aids operation by allowing fast and easy volume setting. This feature removes the need to lock the dial after setting the volume, and virtually eliminates volume drifting. A smooth, continuous, and adjustable micrometer replaces standard click-stop versions, allowing desired volumes to be dialed in for precise measurement. The tip ejector is one-touch attachable and detachable, and easily removeable for cleaning and maintenance.